The main objective of this research is to determine the effectiveness of microbial consortia in beer wastewater treatment. The research was initiated with the isolation of soil microbial consortium that has been contaminated by beer waste water, followed by the selection of the best potential microbial beer wastewater treatment. At the end, the selection of the best microbial consortium was tested in beer wastewater treatment based on pollutant parameters namely biochemical oxygen demand (BOD), chemical oxygen demand (COD) and total suspended solid (TSS). The most effective combination of microbial consortia to reduce the value of TSS, BOD, and COD is the mixed culture combination of Cronobacter sp. strain NGS4, Pseudomonas fluorescent NGS5, and Aeromonas sp. strain NGS7. After 12 days of treatment the value of the COD, BOD and TSS are 633,69±48,18 with degradation rate 66,06%; 199,09±87,82 with degradation rate 78,91%; and 848,9±206,61 with degradation rate 90,50% respectively.