Ground water samples of the selected locations in Dhule city were analyzed in respect of physico-chemical aspects in order to determine the potability of the water and call for same effective measures to be taken to minimize the adverse impact on human health. The avarage values of assessment were compared with the standards given by WHO, ISI and ICMR. It was found from present study that there are variations in many physico-chemical parameters. The sample S-1 and S3 were found within the possible limits, while S-2 and S-4 shows large variations and found to be exceeding their acceptable limits of standards indicating poor potability due to contamination from sewage.