Ground water quality and its impact on human health in and around Mangalam, near Tirupathi, India was assessed. Water samples were collected from 8 different areas in and around Mangalam and analyzed for physicochemical parameters such as pH, electrical conductivity, total dissolved solids, total hardness, calcium, chlorides, sulphates, nitrates and dissolved oxygen. The found values of physicochemical parameters were compared with the World Health Organisation water quality standards. Based on the analysis, it was found that ground water of some of the areas was polluted and not suitable for drinking purpose. Thus the ground water of the area needs purification before drinking.