To assess and evaluate the water quality of Bhopal City, biochemical analysis of drinking water i.e. bore-well’s has been studied seasonally during 2006-07. The study area for this purpose has been chosen is T.T. Nagar and Bhadbhada road of Bhopal. Two readings of analysis have been observed in one season for preliminary analysis of water quality index. The parameters for study are temperature, pH, EC, Free CO2, Chloride, total alkalinity, total hardness, Ca-H, Mg-H, D.O., B.O.D., C.O.D., NO3-, SO42-, analyzed at different sampling stations.