The aim of this manuscript is to review and conceptualization of electricity generation from solid waste using Microbial Fuel Cells (MFCs) technology. MFCs technology has an ample future for both waste remediation and renewable energy generation due to an aerobic microbe produces less sludge in MFCs compared with conventional methods. Electricity can be generated from different organic matters such as fatty acids, proteins, wastewater, and carbohydrates etc. Elegant energy can be generated which helps for compensating the costs. The performance of MFCs depends on the system architecture, internal resistance, species and amount of bacteria on the anode, type of organic matter, chemical characteristics of the medium (pH, solution conductivity and chemical concentration) and the electrode surface characteristics. One set of practical experiment was performed using single chamber MFCs and the power generation along with COD removal was measured. The results show significant power generation and effective COD removal parallel in MFC cell. This study will help in design and research for renewable energy production and waste management.